ST3GAL6 Antikörper (C-Term)

Produktnummer ABIN500813

Produktdetails anti-ST3GAL6 Antikörper

Target: ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ST3GAL6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Spezifität: This antibody detects ST3GAL6.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and Rat

Aufreinigung: Peptide Affinity Chromatography

Immunogen: ST3gal6 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of Human ST3gal6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ST3GAL6

Target: ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))

Andere Bezeichnung: ST3GAL6 (ST3GAL6 Produkte)

Synonyme: SIAT10 antikoerper, ST3GALVI antikoerper, 1700023B24Rik antikoerper, AI930218 antikoerper, AW552396 antikoerper, Siat10 antikoerper, St3galVI antikoerper, ST3GAL-VI antikoerper, ST3 beta-galactoside alpha-2,3-sialyltransferase 6 antikoerper, ST3GAL6 antikoerper, St3gal6 antikoerper

Hintergrund: Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.Synonyms: 3-sialyltransferase, 3-sialyltransferase VI, CMP-NeuAc:beta-galactoside alpha-2, SIAT10, ST3Gal VI, ST3GalVI, Sialyltransferase 10, Type 2 lactosamine alpha-2

Gen-ID: 10402

NCBI Accession: NP_006091

Pathways: Glycosaminoglycan Metabolic Process