PCDHB11 Antikörper (AA 141-240) (AbBy Fluor® 680)

Produktnummer ABIN5008437

Produktdetails anti-PCDHB11 Antikörper (AbBy Fluor® 680)

Target: PCDHB11 (Protocadherin beta 11 (PCDHB11))

Bindungsspezifität: AA 141-240

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHB11 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHB11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PCDHB11

Target: PCDHB11 (Protocadherin beta 11 (PCDHB11))

Andere Bezeichnung: PCDHB11 (PCDHB11 Produkte)

Synonyme: ME2 antikoerper, PCDH-BETA11 antikoerper, Pcdhb5E antikoerper, PcdhbK antikoerper, protocadherin beta 11 antikoerper, PCDHB11 antikoerper, Pcdhb11 antikoerper

Hintergrund:

Synonyms: MGC138337, Cadherin ME2, ME2, MGC138337, MGC142171, MGC142171, PCDBB_HUMAN, PCDH beta 11, PCDH BETA11, PCDH-beta-11, PCDHB11, Protocadherin beta 11, Protocadherin beta-11.

Background: PCDHB11 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. PCDHB11 clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Gen-ID: 56125