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TBC1D1 Antikörper (C-Term)
TBC1D1
Reaktivität: Human
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-TBC1D1 Antikörper
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Target
Alle TBC1D1 Antikörper anzeigen
TBC1D1
(TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))
Bindungsspezifität
Alle Epitope für TBC1D1 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für TBC1D1 Antikörper
Human
Wirt
Alle Wirte für TBC1D1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TBC1D1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für TBC1D1 Antikörper
Dieser TBC1D1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TBC1D1 Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Spezifität
This antibody detects TBC1D1 at C-term.
Kreuzreaktivität (Details)
Species reactivity (tested):Human
Aufreinigung
Peptide afiinity chromatography
Immunogen
TBC1D1 antibody was raised against a 22 amino acid peptide from near the carboxy terminus of human TBC1D1.
Isotyp
IgG
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Discover our top product TBC1D1 Primärantikörper
Alternativen
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anti-TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1) (AA 612-661) antibody
TBC1D1
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Affe
WB, IHC, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
ELISA. Western blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu TBC1D1
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Target
TBC1D1
(TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))
Andere Bezeichnung
TBC1D1 (TBC1D1 Produkte )
Synonyme
TBC1D1 antikoerper, TBC antikoerper, TBC1 antikoerper, 1110062G02Rik antikoerper, AI385682 antikoerper, AW555803 antikoerper, Tbc1 antikoerper, mKIAA1108 antikoerper, TBC1 domain family member 1 antikoerper, TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 antikoerper, TBC1 domain family, member 1 antikoerper, TBC1D1 antikoerper, tbc1d1 antikoerper, LOC100523386 antikoerper, Tbc1d1 antikoerper
Hintergrund
TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain and presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2/USP6, yeast Bub2, and CDC16. TBC1D1 and TBC1D4 (AS160) have been demonstrated to be Rab GAPs (GTPase-activating proteins) that link upstream to Akt and phosphoinositide 3-kinase and downstream to Rabs involved in trafficking of GLUT4 vesicles. TBC1D1 regulates insulin-mediated GLUT4 translocation through its GAP activity, and is a likely Akt substrate. Mutations in the Tbc1d1 gene lead to some cases of severe human obesity.Synonyms: KIAA1108, TBC1 domain family member 1
Gen-ID
23216
NCBI Accession
NP_055988
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