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PHOX2A Antikörper (AA 41-140) (AbBy Fluor® 680)

PHOX2A Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN5008768
  • Target Alle PHOX2A Antikörper anzeigen
    PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
    Bindungsspezifität
    • 14
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 41-140
    Reaktivität
    • 31
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    Human
    Wirt
    • 27
    • 3
    • 1
    Kaninchen
    Klonalität
    • 29
    • 2
    Polyklonal
    Konjugat
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PHOX2A Antikörper ist konjugiert mit AbBy Fluor® 680
    Applikation
    • 25
    • 12
    • 12
    • 11
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PHOX2A
    Isotyp
    IgG
    Top Product
    Discover our top product PHOX2A Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
    Andere Bezeichnung
    PHOX2A/CFEOM2 (PHOX2A Produkte)
    Synonyme
    ARIX antikoerper, CFEOM2 antikoerper, FEOM2 antikoerper, NCAM2 antikoerper, PMX2A antikoerper, Arix antikoerper, Phox2 antikoerper, Pmx2 antikoerper, Pmx2a antikoerper, arix antikoerper, sou antikoerper, zgc:77364 antikoerper, phox2 antikoerper, xphox2a antikoerper, paired like homeobox 2a antikoerper, paired-like homeobox 2a antikoerper, paired like homeobox 2a S homeolog antikoerper, PHOX2A antikoerper, Phox2a antikoerper, phox2a antikoerper, phox2a.S antikoerper
    Hintergrund

    Synonyms: Aristaless homeobox Drosophila fibrosis of extraocular muscles congenital 2 autosomal recessive, Aristaless homeobox gene homolog Drosophila, Aristaless homeobox homolog, Aristaless homeobox protein homolog, ARIX 1 homeodomain protein, ARIX, Arix homeodomain protein, ARIX1 homeodomain protein, CFEOM 2, CFEOM2, FEOM 2, FEOM2, Fibrosis of extraocular muscles congenital 2 autosomal recessive, MGC52227, NCAM 2, NCAM2, Paired like aristaless Homeobox 2A, Paired like homeobox 2a, Paired mesoderm homeobox 2a, Paired mesoderm homeobox protein 2A, Paired-like homeobox 2A, PHOX 2A, Phox2, Phox2a, PHX2A_HUMAN, Pmx 2a, Pmx2, Pmx2a.

    Background: Phox2a (also designated Arix1) and Phox2b are closely related, paired-homeodomain transcription factors that are necessary for neuronal differentiation throughout the developing sympathetic, parasympathetic and enteric ganglia. All enteric nervous system cells evolve from the neural crest, and all cells that are undifferentiated initially express Phox2b. The cells that begin to differentiate along a neuronal lineage continue to express Phox2b, and begin to express Phox2a. Phox2b is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, Phox2a controls only the differentiation of the main noradrenergic center of the brain, the locus ceruleus. Both Phox2a and Phox2b are crucial for the regulation of endogenous tyrosine hydroxylase and dopamine-beta hydroxylase, which are transiently expressed in neural crest cells. In addition, Phox2 proteins are sufficient to promote sympathetic neuron generation. The gene which encodes Phox2a maps to human chromosome 11q13.3-q13.4.

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