PKA Antikörper (AA 17-100) (AbBy Fluor® 750)

Produktnummer ABIN5008869

Produktdetails anti-PKA Antikörper (AbBy Fluor® 750)

Target: PKA (Protein Kinase A (PKA))

Bindungsspezifität: AA 17-100

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKA Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from bovine PKA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PKA

Target: PKA (Protein Kinase A (PKA))

Andere Bezeichnung: PKA alpha + beta (PKA Produkte)

Synonyme: PKCD antikoerper, Pkaca antikoerper, Cs-PKA antikoerper, PKCA1 antikoerper, PKA antikoerper, protein kinase, cAMP dependent, catalytic, alpha antikoerper, protein kinase cAMP-activated catalytic subunit alpha antikoerper, Prkaca antikoerper, PRKACA antikoerper

Hintergrund:

Synonyms: cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta, PRKACB

Background: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, and differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (By similarity).

Gen-ID: 282323

UniProt: P05131

Pathways: SARS-CoV-2 Protein Interaktom