PPM1D Antikörper (AA 201-300) (AbBy Fluor® 750)
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- Target Alle PPM1D Antikörper anzeigen
- PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
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Bindungsspezifität
- AA 201-300
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PPM1D Antikörper ist konjugiert mit AbBy Fluor® 750
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Cow,Pig,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PPM1D
- Isotyp
- IgG
- Top Product
- Discover our top product PPM1D Primärantikörper
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- Applikationshinweise
- IF(ICC) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
- Andere Bezeichnung
- PPM1D (PPM1D Produkte)
- Synonyme
- PP2C-DELTA antikoerper, WIP1 antikoerper, AV338790 antikoerper, Wip1 antikoerper, zgc:103518 antikoerper, ppm1d antikoerper, wu:fj44c08 antikoerper, zgc:55836 antikoerper, zgc:77316 antikoerper, protein phosphatase, Mg2+/Mn2+ dependent 1D antikoerper, protein phosphatase 1D magnesium-dependent, delta isoform antikoerper, protein phosphatase, Mg2+/Mn2+ dependent, 1D antikoerper, protein phosphatase, Mg2+/Mn2+ dependent, 1Db antikoerper, protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog antikoerper, protein phosphatase, Mg2+/Mn2+ dependent, 1Da antikoerper, PPM1D antikoerper, Ppm1d antikoerper, ppm1db antikoerper, ppm1d.L antikoerper, ppm1da antikoerper
- Hintergrund
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Synonyms: WIP1, PP2C-DELTA, Protein phosphatase 1D, Protein phosphatase 2C isoform delta, Protein phosphatase magnesium-dependent 1 delta, p53-induced protein phosphatase 1, PPM1D
Background: Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.
- Gen-ID
- 8493
- UniProt
- O15297
- Pathways
- p53 Signalweg, Zellzyklus
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