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PTCHD2 Antikörper (AA 401-500) (AbBy Fluor® 680)

PTCHD2 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN5009358
  • Target Alle PTCHD2 Antikörper anzeigen
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Bindungsspezifität
    • 14
    • 9
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    Reaktivität
    • 38
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    Human
    Wirt
    • 38
    Kaninchen
    Klonalität
    • 38
    Polyklonal
    Konjugat
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PTCHD2 Antikörper ist konjugiert mit AbBy Fluor® 680
    Applikation
    • 34
    • 19
    • 12
    • 12
    • 8
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PTCHD2/DISP3
    Isotyp
    IgG
    Top Product
    Discover our top product PTCHD2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Andere Bezeichnung
    PTCHD2/DISP3 (PTCHD2 Produkte)
    Synonyme
    DISP3 antikoerper, G630052C06Rik antikoerper, RNDEu-2 antikoerper, RGD1305820 antikoerper, dispatched RND transporter family member 3 antikoerper, patched domain-containing protein 2 antikoerper, si:dkey-32e23.6 antikoerper, DISP3 antikoerper, LOC100082708 antikoerper, si:dkey-32e23.6 antikoerper, disp3 antikoerper, Disp3 antikoerper
    Hintergrund

    Synonyms: DISP3, Dispatched, drosophila, homolog of, 3, G630052C06Rik, hCG_24779, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3, Ptchd2, PTHD2_HUMAN, RGD1305820, RND-type protein RNDEu-2, RNDEu-2, patched domain containing 2, RP23-157B15.1.

    Background: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

    Gen-ID
    57540
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