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TLR11 Antikörper (C-Term)

Tlr11 Reaktivität: Maus WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500942
  • Target Alle TLR11 (Tlr11) Antikörper anzeigen
    TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))
    Bindungsspezifität
    • 3
    • 3
    • 2
    • 1
    • 1
    C-Term
    Reaktivität
    • 7
    • 4
    • 3
    • 3
    • 1
    Maus
    Wirt
    • 10
    • 1
    Kaninchen
    Klonalität
    • 10
    • 1
    Polyklonal
    Konjugat
    • 7
    • 3
    • 1
    Dieser TLR11 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects TLR11 at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Mouse
    Aufreinigung
    Ion exchange chromatography
    Immunogen
    TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy-terminus of mouse TLR11.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 0.5 to 1 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))
    Andere Bezeichnung
    TLR11 (Tlr11 Produkte)
    Synonyme
    RGD1564460 antikoerper, Gm287 antikoerper, toll-like receptor 11 antikoerper, Tlr11 antikoerper
    Hintergrund
    Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).Synonyms: Gm287, Toll-like receptor 11
    Gen-ID
    239081
    NCBI Accession
    NP_991388
    Pathways
    Activation of Innate immune Response
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