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TLR8 Antikörper (Middle Region)

TLR8 Reaktivität: Human, Maus WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500964
  • Target Alle TLR8 Antikörper anzeigen
    TLR8 (Toll-Like Receptor 8 (TLR8))
    Bindungsspezifität
    • 20
    • 15
    • 8
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 81
    • 44
    • 33
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 78
    • 13
    • 1
    Kaninchen
    Klonalität
    • 79
    • 13
    Polyklonal
    Konjugat
    • 33
    • 10
    • 9
    • 8
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TLR8 Antikörper ist unkonjugiert
    Applikation
    • 67
    • 41
    • 25
    • 13
    • 13
    • 11
    • 11
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects CD288 / TLR8 at center.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse.
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8.
    Isotyp
    IgG
    Top Product
    Discover our top product TLR8 Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: 0.5 to 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, 0.02 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TLR8 (Toll-Like Receptor 8 (TLR8))
    Andere Bezeichnung
    CD288 / TLR8 (TLR8 Produkte)
    Synonyme
    CD288 antikoerper, toll like receptor 8 antikoerper, toll-like receptor 8 antikoerper, TLR8 antikoerper, Tlr8 antikoerper
    Hintergrund
    Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). Like TLR7, TLR8 is localized to endosomal or lysosomal compartments (6) and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA (7). Human but not murine TLR8 confers responsiveness to the antiviral compound R-848 (8).Synonyms: Toll-like receptor 8, UNQ249/PRO286
    Gen-ID
    51311
    NCBI Accession
    NP_619542
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
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