TLR8 Antikörper (Middle Region)
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- Target Alle TLR8 Antikörper anzeigen
- TLR8 (Toll-Like Receptor 8 (TLR8))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TLR8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects CD288 / TLR8 at center.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse.
- Aufreinigung
- Peptide affinity chromatography
- Immunogen
- TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8.
- Isotyp
- IgG
- Top Product
- Discover our top product TLR8 Primärantikörper
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- Applikationshinweise
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ELISA. Western blot: 0.5 to 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS, 0.02 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- TLR8 (Toll-Like Receptor 8 (TLR8))
- Andere Bezeichnung
- CD288 / TLR8 (TLR8 Produkte)
- Synonyme
- CD288 antikoerper, toll like receptor 8 antikoerper, toll-like receptor 8 antikoerper, TLR8 antikoerper, Tlr8 antikoerper
- Hintergrund
- Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). Like TLR7, TLR8 is localized to endosomal or lysosomal compartments (6) and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA (7). Human but not murine TLR8 confers responsiveness to the antiviral compound R-848 (8).Synonyms: Toll-like receptor 8, UNQ249/PRO286
- Gen-ID
- 51311
- NCBI Accession
- NP_619542
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
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