Receptor Accessory Protein 1 Antikörper (AA 53-150) (AbBy Fluor® 750)
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- Target Alle Receptor Accessory Protein 1 (REEP1) Antikörper anzeigen
- Receptor Accessory Protein 1 (REEP1)
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Bindungsspezifität
- AA 53-150
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Receptor Accessory Protein 1 Antikörper ist konjugiert mit AbBy Fluor® 750
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human REEP1
- Isotyp
- IgG
- Top Product
- Discover our top product REEP1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Receptor Accessory Protein 1 (REEP1)
- Andere Bezeichnung
- REEP1 (REEP1 Produkte)
- Synonyme
- C2orf23 antikoerper, HMN5B antikoerper, SPG31 antikoerper, D6Ertd253e antikoerper, RGD1305230 antikoerper, receptor accessory protein 1 antikoerper, REEP1 antikoerper, Reep1 antikoerper
- Hintergrund
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Synonyms: C2orf23, Chromosome 2 open reading frame 23, FLJ13110, Receptor accessory protein 1, Receptor expression-enhancing protein 1, Reep1, REEP1_HUMAN, SPG31.
Background: Transport of G protein-coupled receptors (GPCRs) to the cell surface membrane is critical for receptor-ligand recognition. Mammalian GPCR odorant receptors (ORs), when heterologously expressed in cells, are poorly expressed on the cell surface. REEP1 (receptor expression-enhancing protein 1), is a 201 amino acid multi-pass mitochondrion membrane protein that belongs to the DP1 family. REEP1 interacts with odorant receptor proteins and may enhance the cell surface expression of odorant receptors. Mutations in the REEP1 gene are the third most common cause of hereditary spastic paraplegia (HSP) after spastin and atlastin gene mutations. Mutations in the REEP1 gene also cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. The REEP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana and rice, and maps to human chromosome 2p11.2.
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