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TMEM38A Antikörper (C-Term)

TMEM38A Reaktivität: Human, Ratte, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500984
  • Target Alle TMEM38A Antikörper anzeigen
    TMEM38A (Transmembrane Protein 38A (TMEM38A))
    Bindungsspezifität
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 8
    • 1
    Kaninchen
    Klonalität
    • 9
    Polyklonal
    Konjugat
    • 9
    Dieser TMEM38A Antikörper ist unkonjugiert
    Applikation
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects TMEM38A.
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    TMEM38A antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human TMEM38A.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TMEM38A (Transmembrane Protein 38A (TMEM38A))
    Andere Bezeichnung
    TMEM38A (TMEM38A Produkte)
    Synonyme
    zgc:77831 antikoerper, MGC75707 antikoerper, TMEM38A antikoerper, TRIC-A antikoerper, TRICA antikoerper, 1110001E17Rik antikoerper, AI413399 antikoerper, mg33a antikoerper, RGD1307901 antikoerper, Srp-27 antikoerper, transmembrane protein 38A antikoerper, transmembrane protein 38a antikoerper, transmembrane protein 38A L homeolog antikoerper, tmem38a antikoerper, CpipJ_CPIJ011791 antikoerper, CpipJ_CPIJ013655 antikoerper, TMEM38A antikoerper, Tmem38a antikoerper, tmem38a.L antikoerper
    Hintergrund
    TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure, the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.Synonyms: TRIC-A, TRICA, Transmembrane protein 38A, Trimeric intracellular cation channel type A
    Gen-ID
    79041
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