RPGRIP1L Antikörper (AA 41-140) (AbBy Fluor® 680)

Produktnummer ABIN5010048

Produktdetails anti-RPGRIP1L Antikörper (AbBy Fluor® 680)

Target: RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

Bindungsspezifität: AA 41-140

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPGRIP1L Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RPGRIP1L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RPGRIP1L

Target: RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

Andere Bezeichnung: RPGRIP1L (RPGRIP1L Produkte)

Synonyme: si:ch1073-301i20.1 antikoerper, mks5 antikoerper, cors3 antikoerper, jbts7 antikoerper, nphp8 antikoerper, CORS3 antikoerper, FTM antikoerper, JBTS7 antikoerper, MKS5 antikoerper, NPHP8 antikoerper, 1700047E16Rik antikoerper, 4931437C01 antikoerper, Ftm antikoerper, Nphp8 antikoerper, RGD1311099 antikoerper, RPGRIP1 like antikoerper, RPGRIP1-like antikoerper, Protein fantom antikoerper, Rpgrip1-like antikoerper, RPGRIP1L antikoerper, rpgrip1l antikoerper, mks-5 antikoerper, Rpgrip1l antikoerper

Hintergrund:

Synonyms: CORS 3, CORS3, Fantom, FTM, JBTS 1, JBTS 7, JBTS1, JBTS7, Joubert syndrome 1, Joubert syndrome 7, Meckel syndrome, type 1, RPGRIP1-like, Meckel syndrome, type 5, MKS 5, MKS5, NPHP 8, NPHP8, nephrocystin 8, Protein fantom, Retinitis pigmentosa GTPase regulator interacting protein 1 like, RPGR interacting protein 1 like protein, RPGRIP1 like protein, FTM_HUMAN.

Background: RPGRIP1L is a 1,315 amino acid protein that belongs to the RPGRIP1 family and is thought to function in programmed cell death, craniofacial development and formation of the left-right axis. Existing as two alternatively spliced isoforms that localize to the cytoplasm, cytoskeleton, centrosome and cilium basal body, RPGRIP1L interacts with nephrocystin-4 and is moderately expressed in brain, retina and kidney. Containing two C2 domains, RPGRIP1L is encoded by a gene that maps to human chromosome 16q12.2. Defects in the gene encoding RPGRIP1L are the cause of Joubert syndrome type 7 (JBTS7), COACH syndrome (COACHS) and Meckel syndrome type 5 (MKS5).

Pathways: DNA Replication, Regulation of G-Protein Coupled Receptor Protein Signaling, Synthesis of DNA