Tarbp1 antikoerper, Gm179 antikoerper, TARBP1 antikoerper, TRM3 antikoerper, TRP-185 antikoerper, TRP185 antikoerper, TAR RNA binding protein 1 antikoerper, TAR (HIV-1) RNA binding protein 1 antikoerper, Tarbp1 antikoerper, TARBP1 antikoerper, tarbp1 antikoerper
Hintergrund
The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1alpha (EF-1alpha), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.Synonyms: Probable methyltransferase TARBP1, TAR RNA-binding protein 1, TAR RNA-binding protein of 185 kDa, TRM3, TRP-185, TRP185