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KCNK18 Antikörper (Center)

KCNK18 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN501034
  • Target Alle KCNK18 Antikörper anzeigen
    KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    Center
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 22
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCNK18 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 13
    • 13
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    TRESK antibody was raised against a 17 amino acid peptide from near the center of human TRESK.
    Isotyp
    IgG
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    Discover our top product KCNK18 Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
    Andere Bezeichnung
    KCNK18 (KCNK18 Produkte)
    Synonyme
    K2p18.1 antikoerper, MGR13 antikoerper, TRESK antikoerper, TRESK-2 antikoerper, TRESK2 antikoerper, TRIK antikoerper, Gm781 antikoerper, Tresk antikoerper, Tresk-2 antikoerper, Trik antikoerper, potassium two pore domain channel subfamily K member 18 antikoerper, potassium channel, subfamily K, member 18 antikoerper, KCNK18 antikoerper, Kcnk18 antikoerper
    Hintergrund
    TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.Synonyms: KCNK18, Potassium channel subfamily K member 18, TRESK, TRIK, TWIK-related individual potassium channel, TWIK-related spinal cord potassium channel
    Gen-ID
    338567
    NCBI Accession
    NP_862823
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