SKA1 Antikörper (AA 181-255) (AbBy Fluor® 750)
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- Target Alle SKA1 Antikörper anzeigen
- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
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Bindungsspezifität
- AA 181-255
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SKA1 Antikörper ist konjugiert mit AbBy Fluor® 750
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SKA1
- Isotyp
- IgG
- Top Product
- Discover our top product SKA1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
- Andere Bezeichnung
- SKA1 (SKA1 Produkte)
- Synonyme
- C18H18orf24 antikoerper, C18orf24 antikoerper, 2810433K01Rik antikoerper, AV117428 antikoerper, RGD1310784 antikoerper, spindle and kinetochore associated complex subunit 1 antikoerper, SKA1 antikoerper, ska1 antikoerper, Ska1 antikoerper
- Hintergrund
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Synonyms: Ska1, SKA1_HUMAN, Spindle and kinetochore associated complex subunit 1, Spindle and kinetochore associated protein 1, Spindle and kinetochore-associated protein 1, Spindle and KT kinetochore associated 1, Spindle and KT associated 1, C18orf24, MGC10200.
Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.
- Pathways
- M Phase
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