ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle.Synonyms: Chromosome 20 open reading frame 11, TWA1, Two hybrid-associated protein 1 with RanBPM