HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 331-430) Antikörper (AbBy Fluor® 680)
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- Target Alle HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) Antikörper anzeigen
- HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
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Bindungsspezifität
- AA 331-430
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- AbBy Fluor® 680
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Syncytin-2
- Isotyp
- IgG
- Top Product
- Discover our top product Herv-frd Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
- Andere Bezeichnung
- Syncytin 2 (Herv-frd Produkte)
- Synonyme
- ERVFRDE1 antikoerper, GLLL6191 antikoerper, HERV-FRD antikoerper, HERV-W/FRD antikoerper, UNQ6191 antikoerper, envFRD antikoerper, Gm52 antikoerper, Syna antikoerper, endogenous retrovirus group FRD member 1, envelope antikoerper, ERVFRD-1 antikoerper, Ervfrd-1 antikoerper
- Substanzklasse
- Viral Protein
- Hintergrund
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Synonyms: envFRD, UNQ6191, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD, Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD_6p24.1 provirus ancestral Env polyprotein, ERVFRD-1, UNQ6191/PRO20218
Background: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (PubMed:18988732). Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (PubMed:14694139).
- Gen-ID
- 405754
- UniProt
- P60508
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