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TXN2 Antikörper (AA 101-166) (AbBy Fluor® 750)

TXN2 Reaktivität: Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 750
Produktnummer ABIN5011557
  • Target Alle TXN2 Antikörper anzeigen
    TXN2 (Thioredoxin 2 (TXN2))
    Bindungsspezifität
    • 14
    • 9
    • 8
    • 6
    • 3
    • 1
    AA 101-166
    Reaktivität
    • 37
    • 28
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Ratte
    Wirt
    • 51
    • 1
    Kaninchen
    Klonalität
    • 50
    • 2
    Polyklonal
    Konjugat
    • 19
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TXN2 Antikörper ist konjugiert mit AbBy Fluor® 750
    Applikation
    • 38
    • 15
    • 12
    • 12
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Thioredoxin 2
    Isotyp
    IgG
    Top Product
    Discover our top product TXN2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TXN2 (Thioredoxin 2 (TXN2))
    Andere Bezeichnung
    Thioredoxin 2 (TXN2 Produkte)
    Synonyme
    MT-TRX antikoerper, MTRX antikoerper, TRX2 antikoerper, 31884 antikoerper, CG31884 antikoerper, CG3864 antikoerper, DTrx-2 antikoerper, DmTrx-2 antikoerper, DmelTrx-2 antikoerper, Dmel\\CG31884 antikoerper, Trx antikoerper, anon-WO0118547.188 antikoerper, dmtrx-2 antikoerper, 2510006J11Rik antikoerper, AI788873 antikoerper, Trx2 antikoerper, zgc:77127 antikoerper, thioredoxin 2 antikoerper, thioredoxin-2 antikoerper, thiol reductase thioredoxin antikoerper, thioredoxin 2 L homeolog antikoerper, TXN2 antikoerper, Trx-2 antikoerper, LOC409451 antikoerper, VPA0972 antikoerper, VS_RS18125 antikoerper, VCD_000568 antikoerper, VEA_000083 antikoerper, trx2 antikoerper, Txn2 antikoerper, txn2 antikoerper, txn2.L antikoerper
    Hintergrund

    Synonyms: mitochondrial thioredoxin, MT-TRX, MTRX, thioredoxin 2 precursor, Thioredoxin mitochondrial, Thioredoxin2, TRX 2, TRX2, TXN 2, TXN2.

    Background: Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

    Gen-ID
    25828
    Pathways
    Cell RedoxHomeostasis
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