TOR1B Antikörper (AA 281-336) (AbBy Fluor® 680)
-
- Target Alle TOR1B Antikörper anzeigen
- TOR1B (Torsin Family 1, Member B (Torsin B) (TOR1B))
-
Bindungsspezifität
- AA 281-336
-
Reaktivität
- Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser TOR1B Antikörper ist konjugiert mit AbBy Fluor® 680
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Sheep,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Torsin B
- Isotyp
- IgG
- Top Product
- Discover our top product TOR1B Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- TOR1B (Torsin Family 1, Member B (Torsin B) (TOR1B))
- Andere Bezeichnung
- Torsin B (TOR1B Produkte)
- Synonyme
- MGC82811 antikoerper, tor1a antikoerper, 2610016F05Rik antikoerper, DQ1 antikoerper, torsinB antikoerper, torsin family 1, member B (torsin B) L homeolog antikoerper, torsin family 1, member B (torsin B) antikoerper, torsin family 1 member B antikoerper, torsin family 1, member B antikoerper, tor1b.L antikoerper, tor1b antikoerper, TOR1B antikoerper, Tor1b antikoerper
- Hintergrund
-
Synonyms: DQ1, Tor1b, Torsin 1B, TOR1B, FKSG18, Torsin family 1 member B, TOR1B_HUMAN.
Background: TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family. Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins. Via its ability to regulate protein folding, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development. TorsinB contains two PKC (protein kinase C) phosphorylations sites, one ATP binding domain and several conserved cysteines and shares 69 % amino acid identity with TorsinA, a related family member. Defects in the gene encoding TorsinB are associated with torsion dystonia, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body.
-