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Trypsin Inhibitor Antikörper (AA 101-200) (AbBy Fluor® 750)

Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 750
Produktnummer ABIN5012007
  • Target Alle Trypsin Inhibitor Produkte
    Trypsin Inhibitor
    Bindungsspezifität
    AA 101-200
    Reaktivität
    • 14
    • 5
    • 3
    • 1
    Human
    Wirt
    • 23
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Trypsin Inhibitor Antikörper ist konjugiert mit AbBy Fluor® 750
    Applikation
    • 22
    • 12
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Trypsin Inhibitor
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Trypsin Inhibitor
    Abstract
    Trypsin Inhibitor Produkte
    Synonyme
    CRISP11 antikoerper, LCRISP2 antikoerper, GRMZM2G447785 antikoerper, cysteine rich secretory protein LCCL domain containing 2 antikoerper, trypsin inhibitor antikoerper, trophoblast Kunitz domain protein 1 antikoerper, Kazal-type serine proteinase inhibitor 1 antikoerper, Bowman-Birk type bran trypsin inhibitor antikoerper, CRISPLD2 antikoerper, LOC548021 antikoerper, TKDP1 antikoerper, Spi1 antikoerper, LOC100284348 antikoerper
    Hintergrund

    Synonyms: Peptidase inhibitor 15, PI-15, 25 kDa trypsin inhibitor, p25TI, Cysteine-rich secretory protein 8, CRISP-8, SugarCrisp, PI15_HUMAN.

    Background: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-8 (Cysteine-rich secretory protein 8), also known as PI15 (Peptidase inhibitor 15), P25TI or SugarCrisp, is a 258 amino acid secreted protein that belongs to the CRISP family. Expressed at low levels in thyroid, prostate, salivary and mammary tissue, CRISP-8 functions as a serine protease inhibitor that exhibits weak inhibitory action against Trypsin, a serine protease found in the digestive system. In addition to its role as a protease inhibitor, CRISP-8 is secreted in neuroblastoma and glioblastoma cell lines, suggesting a role for CRISP-8 in tumor formation and metastasis within the central nervous system.

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