TUSC2 Antikörper (AA 31-100) (AbBy Fluor® 680)
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- Target Alle TUSC2 Antikörper anzeigen
- TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))
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Bindungsspezifität
- AA 31-100
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TUSC2 Antikörper ist konjugiert mit AbBy Fluor® 680
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TUSC2
- Isotyp
- IgG
- Top Product
- Discover our top product TUSC2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))
- Andere Bezeichnung
- TUSC2 (TUSC2 Produkte)
- Synonyme
- C3orf11 antikoerper, FUS1 antikoerper, PAP antikoerper, PDAP2 antikoerper, TUSC2 antikoerper, 1190001E22Rik antikoerper, AA407686 antikoerper, Fus1 antikoerper, Lgcc antikoerper, Pdap2 antikoerper, zgc:92701 antikoerper, zgc:153746 antikoerper, tumor suppressor candidate 2 antikoerper, tumor suppressor candidate 2 L homeolog antikoerper, tumor suppressor candidate 2b antikoerper, tumor suppressor candidate 2a antikoerper, TUSC2 antikoerper, tusc2.L antikoerper, Tusc2 antikoerper, tusc2b antikoerper, tusc2a antikoerper
- Hintergrund
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Synonyms: C3orf11, FUS1, Fusion 1 protein, PAP, PDAP2, PDGFA associated protein 2, Tumor suppressor candidate 2, TUSC 2, TUSC2_HUMAN.
Background: TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21.3 region where allele losses and genetic alterations occur early and frequently for many human cancers. Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions. Restoration of TUSC2 function in 3p21.3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics. TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, PDGFR, AKT, c-Abl, and c-Kit.
- Gen-ID
- 11334
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