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RAX Antikörper (AA 100-313)

RAX Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5027505
  • Target Alle RAX Antikörper anzeigen
    RAX (Retina and Anterior Neural Fold Homeobox (RAX))
    Bindungsspezifität
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 100-313
    Reaktivität
    • 16
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 11
    • 5
    Kaninchen
    Klonalität
    • 11
    • 5
    Polyklonal
    Konjugat
    • 14
    • 1
    • 1
    Dieser RAX Antikörper ist unkonjugiert
    Applikation
    • 14
    • 8
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    Protein A Chromatography
    Immunogen
    A partial length recombinant RAX protein (amino acids 100-313) was used as the immunogen for this antibody.
    Isotyp
    IgG
    Top Product
    Discover our top product RAX Primärantikörper
  • Applikationshinweise
    WB: 1-2 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    RAX (Retina and Anterior Neural Fold Homeobox (RAX))
    Andere Bezeichnung
    RAX (RAX Produkte)
    Synonyme
    MCOP3 antikoerper, RX antikoerper, 7530406A22Rik antikoerper, E130303K03Rik antikoerper, Rx antikoerper, ey-1 antikoerper, ey1 antikoerper, RAX antikoerper, rx antikoerper, rx1 antikoerper, Rx2A antikoerper, Xrax antikoerper, Xrx1 antikoerper, rax antikoerper, CG10052 antikoerper, DRx antikoerper, Dmel\\CG10052 antikoerper, Drx antikoerper, E97 antikoerper, PPH17 antikoerper, W60 antikoerper, bk50 antikoerper, drx antikoerper, wom antikoerper, Xrx2 antikoerper, rax-a antikoerper, rax1 antikoerper, rx1a antikoerper, rx2a antikoerper, retina and anterior neural fold homeobox antikoerper, Retinal Homeobox antikoerper, retina and anterior neural fold homeobox L homeolog antikoerper, retina and anterior neural fold homeobox S homeolog antikoerper, RAX antikoerper, Rax antikoerper, rax antikoerper, Rx antikoerper, rax.L antikoerper, rax.S antikoerper
    Hintergrund
    RAX or PRKRA (retina and anterior neural fold homeobox) is a homeobox-containing transcription factor. It plays an important role in eye development by regulating the initial specification of retinal cells. In the absence of double-stranded RNA, RAX activates EIF2AK2/PKR, so as to phosphorylate EIF2S1/EFI2-alpha leading to inhibition of translation and induction of apoptosis. RAX has been reported to be essential for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia and coloboma. RAX is expressed in blood, bone, brain, spleen and adipose tissues.
    Molekulargewicht
    30 kDa
    Gen-ID
    8575
    UniProt
    O75569
    Pathways
    Regulatorische RNA Pathways
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