SPIB Antikörper (AA 50-260)
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- Target Alle SPIB Antikörper anzeigen
- SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
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Bindungsspezifität
- AA 50-260
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPIB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Aufreinigung
- Protein A Chromatography
- Immunogen
- A partial length recombinant Spi-B protein (amino acids 50-260) was used as the immunogen for this antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product SPIB Primärantikörper
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- Applikationshinweise
- WB: 2-4 μg/mL, IHC: 5 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
- Andere Bezeichnung
- Spi-B (SPIB Produkte)
- Synonyme
- spi-b antikoerper, spib antikoerper, spiba antikoerper, SPI-B antikoerper, B42b-like antikoerper, Spi-B antikoerper, Spi-B transcription factor L homeolog antikoerper, Spi-B transcription factor antikoerper, Spi-B transcription factor (Spi-1/PU.1 related) antikoerper, spib.L antikoerper, SPIB antikoerper, Spib antikoerper
- Hintergrund
- Spi-B belongs to the ETS family transcription containing a conserved ETS domain which specifically binds to a purine-rich DNA sequence called the PU-box (5'-GAGGAA-3'). Spi-B has two known isoforms (28 and 18 kDa) localized in nucleus and cytoplasm. Spi-B contains two transactivation domains (TAD) at the N- terminal end which may be required for transcriptional activation of the target genes. Spi-B is involved in development of plasmacytoid dendritic cells (natural interferon producing cells) and B-cell development. Spi-B acts as a lymphoid specific enhancer. Spi-B is highly expressed in plasmacytoid dendritic cells (pDCs), B-cells and stem cell populations of the liver.
- Molekulargewicht
- 28 kDa
- Gen-ID
- 6689
- UniProt
- Q01892
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