TNRC9 antikoerper, cagf9 antikoerper, tnrc9 antikoerper, CAGF9 antikoerper, 500-9 antikoerper, BC052044 antikoerper, C230068E13 antikoerper, Tnrc9 antikoerper, TOX high mobility group box family member 3 antikoerper, TOX3 antikoerper, tox3 antikoerper, Tox3 antikoerper
Hintergrund
TOX high mobility group box family member 3 (TOX-3) is a member of a subfamily of transcription factors that contains a High Mobility Group box (HMG-box), involved in bending and unwinding of DNA and alteration of chromatin structure. It has two transcript variants encoding different isoforms.TOX3 is expressed in estrogen receptor-positive mammary epithelial cells, including progenitor cells and highly expressed in luminal B breast cancers. Its over expression in human oligodendrocytes reduced cellular death under conditions mimicking Spinal cord injury (SCI).