ULK1 Antikörper (AA 567-577) (Biotin)

Produktnummer ABIN5066148

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ULK1 in WB, IF und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ULK1 Antikörper (AA 567-577) (Biotin) (ABIN5066148)

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULK1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-ULK1 Antikörper (Biotin)

Bindungsspezifität: AA 567-577

Spezifität: Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.,Detects ~100 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Peptide Affinity Purified

Immunogen: Synthetic peptide from the mid-protein of Human ULK1 (aa. 567-577)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:1000 dilution of ABIN5066148 was sufficient for detection of ULK1 in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Andere Bezeichnung: ULK1

Hintergrund: UNC-51 like kinase 1 (ULK1) is widely expresed and contains an amino-terminal kinase domain followed by a central proline-serine rich domain and a highly conserved carboxy-terminal domain. It has been linked to axon growth and is essential for autophagy. Structurally, ULK1 is similar to ATG1, and it appears that both Atg1/ULK1 can bind to several ATG proteins regulating phosphorylation states and protein trafficking.

Gen-ID: 8408

NCBI Accession: NP_003556

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagie