WDR45 Antikörper (AA 312-322)

Produktnummer ABIN5066245

Produktdetails anti-WDR45 Antikörper

Target: WDR45 (WD Repeat Domain 45 (WDR45))

Bindungsspezifität: AA 312-322

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDR45 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors.,Detects ~40 kDa.

Kreuzreaktivität: Human, Ratte

Aufreinigung: Peptide Affinity Purified

Immunogen: Synthetic peptide from the C-terminal of Human WIPI4 (aa. 312-322)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:1000 dilution of ABIN5066245 was sufficient for detection of WIPI4 in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu WDR45

Target: WDR45 (WD Repeat Domain 45 (WDR45))

Andere Bezeichnung: WDR45 (WDR45 Produkte)

Synonyme: MGC80694 antikoerper, NBIA4 antikoerper, NBIA5 antikoerper, WDRX1 antikoerper, WIPI-4 antikoerper, WIPI4 antikoerper, C79260 antikoerper, DXImx38e antikoerper, JM5 antikoerper, Sfc19 antikoerper, Wdrx1 antikoerper, zgc:56345 antikoerper, zgc:77017 antikoerper, WD repeat domain 45 S homeolog antikoerper, WD repeat domain 45 antikoerper, wdr45.S antikoerper, WDR45 antikoerper, Wdr45 antikoerper, wdr45 antikoerper

Hintergrund: WIPI-4 is a 360 amino acid protein containing three WD repeats. Existing as three alternatively spliced isoforms, WIPI-4 is ubiquitously expressed but found at highest levels in heart and skeletal muscle. WD repeat proteins are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Diseases associated with this gene include neurodegeneration with brain iron accululation 5 and 4.

Gen-ID: 11152

NCBI Accession: NP_001025067

UniProt: Q9Y484