GDNF Antikörper (Atto 594)
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- Target Alle GDNF Antikörper anzeigen
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GDNF Antikörper ist konjugiert mit Atto 594
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.,Detects ~24 kDa.
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Peptide Affinity Purified
- Immunogen
- Synthetic peptide from the mid-protein of Human GDNF
- Isotyp
- IgG
- Top Product
- Discover our top product GDNF Primärantikörper
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- Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:100)
- IHC (1:50)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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A 1:1000 dilution of ABIN5066753 was sufficient for detection of GDNF in 15 μg of human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
- Andere Bezeichnung
- GDNF (GDNF Produkte)
- Synonyme
- gdnf antikoerper, GDNF antikoerper, AI385739 antikoerper, gdnfa antikoerper, hfb1-gdnf antikoerper, ATF1 antikoerper, ATF2 antikoerper, HFB1-GDNF antikoerper, HSCR3 antikoerper, glial cell derived neurotrophic factor antikoerper, glial cell derived neurotrophic factor a antikoerper, glial cell line derived neurotrophic factor antikoerper, glial cell derived neurotrophic factor L homeolog antikoerper, Gdnf antikoerper, gdnfa antikoerper, GDNF antikoerper, gdnf.L antikoerper
- Gen-ID
- 2668
- NCBI Accession
- NP_000505
- UniProt
- P39905
- Pathways
- RTK Signalweg, Synaptic Membrane, Tube Formation, Autophagie, Smooth Muscle Cell Migration
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