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GDNF Antikörper (Biotin)

GDNF Reaktivität: Human WB, IHC, ICC, IF Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN5066760
  • Target Alle GDNF Antikörper anzeigen
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    Reaktivität
    • 83
    • 42
    • 32
    • 16
    • 16
    • 1
    Human
    Wirt
    • 78
    • 6
    • 3
    • 3
    Kaninchen
    Klonalität
    • 76
    • 13
    • 1
    Polyklonal
    Konjugat
    • 40
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GDNF Antikörper ist konjugiert mit Biotin
    Applikation
    • 74
    • 27
    • 25
    • 19
    • 16
    • 13
    • 13
    • 11
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.,Detects ~24 kDa.
    Kreuzreaktivität
    Human, Ratte
    Aufreinigung
    Peptide Affinity Purified
    Immunogen
    Synthetic peptide from the mid-protein of Human GDNF
    Isotyp
    IgG
    Top Product
    Discover our top product GDNF Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • IHC (1:50)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    A 1:1000 dilution of ABIN5066760 was sufficient for detection of GDNF in 15 μg of human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    Andere Bezeichnung
    GDNF (GDNF Produkte)
    Synonyme
    gdnf antikoerper, GDNF antikoerper, AI385739 antikoerper, gdnfa antikoerper, hfb1-gdnf antikoerper, ATF1 antikoerper, ATF2 antikoerper, HFB1-GDNF antikoerper, HSCR3 antikoerper, glial cell derived neurotrophic factor antikoerper, glial cell derived neurotrophic factor a antikoerper, glial cell line derived neurotrophic factor antikoerper, glial cell derived neurotrophic factor L homeolog antikoerper, Gdnf antikoerper, gdnfa antikoerper, GDNF antikoerper, gdnf.L antikoerper
    Gen-ID
    2668
    NCBI Accession
    NP_000505
    UniProt
    P39905
    Pathways
    RTK Signalweg, Synaptic Membrane, Tube Formation, Autophagie, Smooth Muscle Cell Migration
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