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FNIP1 Antikörper (APC)

FNIP1 Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal APC
Produktnummer ABIN5066849
  • Target Alle FNIP1 Antikörper anzeigen
    FNIP1 (Folliculin Interacting Protein 1 (FNIP1))
    Reaktivität
    • 18
    • 1
    • 1
    Human
    Wirt
    • 17
    • 1
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FNIP1 Antikörper ist konjugiert mit APC
    Applikation
    • 12
    • 11
    • 11
    • 10
    • 6
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Strong expression is found in the heart, liver placenta, muscle, nasal mucosa, salivary gland and uvula and moderate expression in kidney and lung. Higher levels detected in clear cell renal cell carcinoma (RCC) and chromophobe RCC than in normal kidney tissue.,Detects ~130 kDa.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Peptide Affinity Purified
    Immunogen
    Synthetic peptide from the mid-protein of Human FNIP1
    Isotyp
    IgG
    Top Product
    Discover our top product FNIP1 Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • IHC (1:50)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    A 1:1000 dilution of ABIN5066849 was sufficient for detection of FNIP1 in 15 μg of mouse kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    FNIP1 (Folliculin Interacting Protein 1 (FNIP1))
    Andere Bezeichnung
    FNIP1 (FNIP1 Produkte)
    Synonyme
    FNIP1 antikoerper, DKFZp468P0310 antikoerper, A730024A03Rik antikoerper, AI838773 antikoerper, AW557298 antikoerper, folliculin interacting protein 1 antikoerper, FNIP1 antikoerper, fnip1 antikoerper, Fnip1 antikoerper
    Hintergrund
    Folliculin-interacting protein 1 (FNIP1) is a co-chaperone of HSP90 (1). It Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways and may regulate the phosphorylation of RPS6KB1 (2). FNIP1 is strongly expressed in the heart, liver placenta, muscle, nasal mucosa, salivary gland, and uvula. Elevated levels of FNIP1 have been detected in renal cell carcinoma (RCC) (3).
    Gen-ID
    96459
    NCBI Accession
    NP_001008738
    UniProt
    Q8TF40
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