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Malondialdehyde Antikörper (PE)

MDA WB, ELISA, ICC, IF, IHC Wirt: Maus Monoclonal 11E3 PE
Produktnummer ABIN5067377
  • Target Alle Malondialdehyde (MDA) Antikörper anzeigen
    Malondialdehyde (MDA)
    Reaktivität
    Bitte anfragen
    Wirt
    • 22
    • 2
    • 1
    Maus
    Klonalität
    • 22
    • 3
    Monoklonal
    Konjugat
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Malondialdehyde Antikörper ist konjugiert mit PE
    Applikation
    • 23
    • 21
    • 21
    • 20
    • 13
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Spezifität
    Specific for MDA conjugated proteins. Does not detect free MDA. Does not cross-react with Acrolein, Crotonaldehyde, Hexanoyl Lysine, 4-HHE, 4-HNE, or Methylglyoxal modified proteins.
    Aufreinigung
    Protein G Purified
    Immunogen
    Synthetic Malondialdehyde modified Keyhole Limpet Hemocyanin (KLH).
    Klon
    11E3
    Isotyp
    IgG1
    Top Product
    Discover our top product MDA Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:50)
    • ELISA (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    A 1:1000 dilution of ABIN5067377 was sufficient for detection of Malondialdehyde in 2 μg of Malondialdehyde conjugated to BSA by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary Antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    Malondialdehyde (MDA)
    Andere Bezeichnung
    Malondialdehyde (MDA Produkte)
    Substanzklasse
    Chemical
    Hintergrund
    Malondialdehyde (MDA) is the biomarker in greatest diagnostic use, due to its molecular stability. This three-carbon, low-molecular weight aldehyde has a strong affinity for amino acids, which results in adduct formation to both free amino acids and proteins. Increased MDA levels have been found at correlating levels in breast cancer, and lung cancer patients. Other diseased states with elevated MDA levels include diabetes and Alzheimer's disease. Multiple laboratory techniques exist for quantification of MDA levels, including the thiobarbituric acid reactive substances (TBARS) assay. In addition to use as a biomarker, MDA has been shown to have mutagenic effects on tissues themselves as adduct formation can result in DNA cross-linking.
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