HLA-ABC Antikörper (APC)
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- Target Alle HLA-ABC Antikörper anzeigen
- HLA-ABC
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Reaktivität
- Human, Pavian, Cynomolgus, Rhesusaffen
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser HLA-ABC Antikörper ist konjugiert mit APC
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Applikation
- Flow Cytometry (FACS)
- Verwendungszweck
- Anti-HLA-ABC APC Antibody
- Produktmerkmale
- Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
- Aufreinigung
- Purified
- Reinheit
- >95 %
- Güteklasse
- GMP Grade
- Immunogen
- Human Leukocytes
- Klon
- W6-32
- Isotyp
- IgG2a, kappa
- Top Product
- Discover our top product HLA-ABC Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- 2-8°C, Conjugated antibodies should never be frozen.
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- Target
- HLA-ABC
- Andere Bezeichnung
- HLA-ABC (HLA-ABC Produkte)
- Synonyme
- HLAA antikoerper, major histocompatibility complex, class I, A antikoerper, HLA-A antikoerper
- Pathways
- T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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