ALOX15 Antikörper (AA 1-662)

Produktnummer ABIN513270

Produktdetails anti-ALOX15 Antikörper

Target: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Bindungsspezifität: AA 1-662

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ALOX15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant ALOX15.

Sequenz: MGLYRIRVST GASLYAGSNN QVQLWLVGQH GEAALGKRLW PARGKETELK VEVPEYLGPL LFVKLRKRHL LKDDAWFCNW ISVQGPGAGD EVRFPCYRWV EGNGVLSLPE GTGRTVGEDP QGLFQKHREE ELEERRKLYR WGNWKDGLIL NMAGAKLYDL PVDERFLEDK RVDFEVSLAK GLADLAIKDS LNVLTCWKDL DDFNRIFWCG QSKLAERVRD SWKEDALFGY QFLNGANPVV LRRSAHLPAR LVFPPGMEEL QAQLEKELEG GTLFEADFSL LDGIKANVIL CSQQHLAAPL VMLKLQPDGK LLPMVIQLQL PRTGSPPPPL FLPTDPPMAW LLAKCWVRSS DFQLHELQSH LLRGHLMAEV IVVATMRCLP SIHPIFKLII PHLRYTLEIN VRARTGLVSD MGIFDQIMST GGGGHVQLLK QAGAFLTYSS FCPPDDLADR GLLGVKSSFY PQDALRLWEI IYRYVEGIVS LHYKTDVAVK DDPELQTWCR EITEIGLQGA QDRGFPVSLQ ARDQVCHFVT MCIFTCTGQH ASVHLGQLDW YSWVPNAPCT MRLPPPTTKD ATLETVMATL PNFHQASLQM SITWQLGRRQ PVMVAVGQHE EEYFSGPEPK AVLKKFREEL AALDKEIEIR NAKLDMPYEY LRPSVVENSV AI

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: ALOX15 (AAH29032, 1 a.a. ~ 662 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 3D8

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ALOX15 Antikörper (ABIN513270)

Gregus, Dumlao, Wei, Norris, Catella, Meyerstein, Buczynski, Steinauer, Fitzsimmons, Yaksh, Dennis: "Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 5, pp. 1939-49, (2013) (PubMed).

Dobrian, Lieb, Ma, Lindsay, Cole, Ma, Chakrabarti, Kuhn, Wohlgemuth, Fontana, Nadler: "Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects." in: Biochemical and biophysical research communications, Vol. 403, Issue 3-4, pp. 485-90, (2010) (PubMed).

Calandria, Marcheselli, Mukherjee, Uddin, Winkler, Petasis, Bazan: "Selective survival rescue in 15-lipoxygenase-1-deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1." in: The Journal of biological chemistry, Vol. 284, Issue 26, pp. 17877-82, (2009) (PubMed).

Details zu ALOX15

Target: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Andere Bezeichnung: ALOX15 (ALOX15 Produkte)

Hintergrund: Full Gene Name: arachidonate 15-lipoxygenase
Synonyms: 15-LOX-1,15-LOX2

Gen-ID: 246

Pathways: Regulation of Actin Filament Polymerization