AKR1C2 Antikörper (AA 224-323)

Produktnummer ABIN514927

Produktdetails anti-AKR1C2 Antikörper

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Bindungsspezifität: AA 224-323

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AKR1C2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant AKR1C2.

Sequenz: EEPWVDPNSP VLLEDPVLCA LAKKHKRTPA LIALRYQLQR GVVVLAKSYN EQRIRQNVQV FEFQLTSEEM KAIDGLNRNV RYLTLDIFAG PPNYPVSDEY

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: AKR1C2 (AAH63574, 224 a.a. ~ 323 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 3C11

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-AKR1C2 Antikörper (ABIN514927)

Hevir, Vouk, Sinkovec, Ribi?-Pucelj, Rižner: "Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 217-26, (2011) (PubMed).

Takahashi, Bains, Pfeifer, Grigliatti, Reid, Riggs: "Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 36, Issue 6, pp. 991-4, (2008) (PubMed).

Details zu AKR1C2

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Andere Bezeichnung: AKR1C2 (AKR1C2 Produkte)

Synonyme: AKR1C-pseudo antikoerper, BABP antikoerper, DD antikoerper, DD2 antikoerper, DDH2 antikoerper, HAKRD antikoerper, HBAB antikoerper, MCDR2 antikoerper, SRXY8 antikoerper, Akr1c21 antikoerper, aldo-keto reductase family 1 member C2 antikoerper, aldo-keto reductase family 1, member C2 antikoerper, AKR1C2 antikoerper, Akr1c2 antikoerper

Hintergrund: Full Gene Name: aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2, bile acid binding protein, 3-alpha hydroxysteroid dehydrogenase, type III)
Synonyms: AKR1C-pseudo,BABP,DD,DD2,DDH2,HAKRD,HBAB,MCDR2

Gen-ID: 1646

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process