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EIF2AK2 Antikörper (AA 1-100)

EIF2AK2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1D11 unconjugated
Produktnummer ABIN519273
  • Target Alle EIF2AK2 Antikörper anzeigen
    EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
    Bindungsspezifität
    • 50
    • 40
    • 11
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 135
    • 77
    • 51
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 129
    • 10
    Maus
    Klonalität
    • 114
    • 25
    Monoklonal
    Konjugat
    • 74
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Dieser EIF2AK2 Antikörper ist unkonjugiert
    Applikation
    • 108
    • 45
    • 41
    • 40
    • 35
    • 29
    • 21
    • 17
    • 10
    • 10
    • 7
    • 4
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Mouse monoclonal antibody raised against a partial recombinant EIF2AK2.
    Sequenz
    MAGDLSAGFF MEELNTYRQK QGVVLKYQEL PNSGPPHDRR FTFQVIIDGR EFPEGEGRSK KEAKNAAAKL AVEILNKEKK AVSPLLLTTT NSSEGLSMGN
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    EIF2AK2 (NP_002750, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Klon
    1D11
    Isotyp
    IgG1
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Liu, Bennett, Cheng, Byrne, Reinhard, May: "PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells." in: Blood, Vol. 121, Issue 17, pp. 3364-74, (2013) (PubMed).

    Cheng, Bennett, Liu, Byrne, Stratford May: "PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis." in: Blood cancer journal, Vol. 3, pp. e144, (2013) (PubMed).

    Bennett, Carruthers, Hui, Kerney, Liu, May: "Increased expression of the dsRNA-activated protein kinase PKR in breast cancer promotes sensitivity to doxorubicin." in: PLoS ONE, Vol. 7, Issue 9, pp. e46040, (2012) (PubMed).

  • Target
    EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
    Andere Bezeichnung
    EIF2AK2 (EIF2AK2 Produkte)
    Hintergrund
    Full Gene Name: eukaryotic translation initiation factor 2-alpha kinase 2
    Synonyms: EIF2AK1,MGC126524,PKR,PRKR
    Gen-ID
    5610
    NCBI Accession
    NM_002759
    Pathways
    DNA Reparatur, ER-Nucleus Signaling, Hepatitis C
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