HIRA Antikörper (AA 1-1017)

Produktnummer ABIN521162

Produktdetails anti-HIRA Antikörper

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Bindungsspezifität: AA 1-1017

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser HIRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: Mouse polyclonal antibody raised against a full-length human HIRA protein.

Sequenz: MKLLKPTWVN HNGKPIFSVD IHPDGTKFAT GGQGQDSGKV VIWNMSPVLQ EDDEKDENIP KMLCQMDNHL ACVNCVRWSN SGMYLASGGD DKLIMVWKRA TYIGPSTVFG SSGKLANVEQ WRCVSILRNH SGDVMDVAWS PHDAWLASCS VDNTVVIWNA VKFPEILATL RGHSGLVKGL TWDPVGKYIA SQADDRSLKV WRTLDWQLET SITKPFDECG GTTHVLRLSW SPDGHYLVSA HAMNNSGPTA QIIEREGWKT NMDFVGHRKA VTVVKFNPKI FKKKQKNGSS AKPSCPYCCC AVGSKDRSLS VWLTCLKRPL VVIHELFDKS IMDISWTLNG LGILVCSMDG SVAFLDFSQD ELGDPLSEEE KSRIHQSTYG KSLAIMTEAQ LSTAVIENPE MLKYQRRQQQ QQLDQKSAAT REMGSATSVA GVVNGESLED IRKNLLKKQV ETRTADGRRR ITPLCIAQLD TGDFSTAFFN SIPLSGSLAG TMLSSHSSPQ LLPLDSSTPN SFGASKPCTE PVVAASARPA GDSVNKDSMN ATSTPAALSP SVLTTPSKIE PMKAFDSRFT ERSKATPGAP ALTSMTPTAV ERLKEQNLVK ELRPRDLLES SSDSDEKVPL AKASSLSKRK LELEVETVEK KKKGRPRKDS RLMPVSLSVQ SPAALTAEKE AMCLSAPALA LKLPIPSPQR AFTLQVSSDP SMYIEVENEV TVVGGVKLSR LKCNREGKEW ETVLTSRILT AAGSCDVVCV ACEKRMLSVF STCGRRLLSP ILLPSPISTL HCTGSYVMAL TAAATLSVWD VHRQVVVVKE ESLHSILAGS DMTVSQILLT QHGIPVMNLS DGKAYCFNPS LSTWNLVSDK QDSLAQCADF RSSLPSQDAM LCSGPLAIIQ GRTSNSGRQA ARLFSVPHVV QQETTLAYLE NQVAAALTLQ SSHEYRHWLL VYARYLVNEG FEYRLREICK DLLGPVHYST GSQWESTVVG LRKRELLKEL LPVIGQNLRF QRLFTECQEQ LDILRDK

Kreuzreaktivität: Human

Produktmerkmale: Antibody reactive against mammalian transfected lysate.

Immunogen: HIRA (NP_003316.3, 1 a.a. ~ 1017 a.a) full-length human protein.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-HIRA Antikörper (ABIN521162)

Jiang, Nguyen, Cao, Chang, Reddel: "HP1-mediated formation of alternative lengthening of telomeres-associated PML bodies requires HIRA but not ASF1a." in: PLoS ONE, Vol. 6, Issue 2, pp. e17036, (2011) (PubMed).

Details zu HIRA

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Andere Bezeichnung: HIRA (HIRA Produkte)

Hintergrund: Full Gene Name: HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
Synonyms: DGCR1,TUP1,TUPLE1

Gen-ID: 7290

NCBI Accession: NM_003325

Pathways: Chromatin Binding