RNF8 Antikörper (AA 1-485)

Produktnummer ABIN522468

Produktdetails anti-RNF8 Antikörper

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Bindungsspezifität: AA 1-485

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser RNF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: Mouse polyclonal antibody raised against a full-length human RNF8 protein.

Sequenz: MGEPGFFVTG DRAGGRSWCL RRVGMSAGWL LLEDGCEVTV GRGFGVTYQL VSKICPLMIS RNHCVLKQNP EGQWTIMDNK SLNGVWLNRA RLEPLRVYSI HQGDYIQLGV PLENKENAEY EYEVTEEDWE TIYPCLSPKN DQMIEKNKEL RTKRKFSLDE LAGPGAEGPS NLKSKINKVS CESGQPVKSQ GKGEVASTPS DNLDPKLTAL EPSKTTGAPI YPGFPKVTEV HHEQKASNSS ASQRSLQMFK VTMSRILRLK IQMQEKHEAV MNVKKQTQKG NSKKVVQMEQ ELQDLQSQLC AEQAQQQARV EQLEKTFQEE EQHLQGLEIA QGEKDLKQQL AQALQEHWAL MEELNRSKKD FEAIIQAKNK ELEQTKEEKE KMQAQKEEVL SHMNDVLENE LQCIICSEYF IEAVTLNCAH SFCSYCINEW MKRKIECPIC RKDIKSKTYS LVLDNCINKM VNNLSSEVKE RRIVLIRERK AKRLF

Kreuzreaktivität: Human

Produktmerkmale: Antibody reactive against mammalian transfected lysate.

Immunogen: RNF8 (NP_003949.1, 1 a.a. ~ 485 a.a) full-length human protein.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-RNF8 Antikörper (ABIN522468)

Hodge, Ismail, Edwards, Hura, Xiao, Tainer, Hendzel, Glover: "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9396-410, (2016) (PubMed).

Yang, Deng, Hau, Liu, Lau, Cheung, Huen, Tsao: "Epstein-Barr virus BZLF1 protein impairs accumulation of host DNA damage proteins at damage sites in response to DNA damage." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 8, pp. 937-50, (2015) (PubMed).

Hau, Deng, Jia, Yang, Tsurumi, Chiang, Huen, Tsao: "Role of ATM in the formation of the replication compartment during lytic replication of Epstein-Barr virus in nasopharyngeal epithelial cells." in: Journal of virology, Vol. 89, Issue 1, pp. 652-68, (2014) (PubMed).

Morris, Boutell, Keppler, Densham, Weekes, Alamshah, Butler, Galanty, Pangon, Kiuchi, Ng, Solomon: "The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress." in: Nature, Vol. 462, Issue 7275, pp. 886-90, (2009) (PubMed).

Details zu RNF8

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Andere Bezeichnung: RNF8 (RNF8 Produkte)

Synonyme: hRNF8 antikoerper, 3830404E21Rik antikoerper, AIP37 antikoerper, RNF8 antikoerper, rnf8 antikoerper, fc66f09 antikoerper, wu:fc66f09 antikoerper, zgc:55936 antikoerper, zgc:77313 antikoerper, ring finger protein 8 antikoerper, ring finger protein 8, E3 ubiquitin protein ligase S homeolog antikoerper, ring finger protein 8, E3 ubiquitin protein ligase L homeolog antikoerper, ring finger protein 8, E3 ubiquitin protein ligase antikoerper, RNF8 antikoerper, Rnf8 antikoerper, rnf8.S antikoerper, rnf8.L antikoerper, rnf8 antikoerper

Hintergrund: Full Gene Name: ring finger protein 8
Synonyms: FLJ12013,KIAA0646

Gen-ID: 9025

NCBI Accession: NM_003958

Pathways: Production of Molecular Mediator of Immune Response