AIM2 Antikörper (AA 1-343)
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- Target Alle AIM2 Antikörper anzeigen
- AIM2 (Absent in Melanoma 2 (AIM2))
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Bindungsspezifität
- AA 1-343
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Polyklonal
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Konjugat
- Dieser AIM2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Verwendungszweck
- Mouse polyclonal antibody raised against a full-length human AIM2 protein.
- Sequenz
- MESKYKEILL LTGLDNITDE ELDRFKFFLS DEFNIATGKL HTANRIQVAT LMIQNAGAVS AVMKTIRIFQ KLNYMLLAKR LQEEKEKVDK QYKSVTKPKP LSQAEMSPAA SAAIRNDVAK QRAAPKVSPH VKPEQKQMVA QQESIREGFQ KRCLPVMVLK AKKPFTFETQ EGKQEMFHAT VATEKEFFFV KVFNTLLKDK FIPKRIIIIA RYYRHSGFLE VNSASRVLDA ESDQKVNVPL NIIRKAGETP KINTLQTQPL GTIVNGLFVV QKVTEKKKNI LFDLSDNTGK MEVLGVRNED TMKCKEGDKV RLTFFTLSKN GEKLQLTSGV HSTIKVIKAK KKT
- Kreuzreaktivität
- Human
- Produktmerkmale
- Antibody reactive against mammalian transfected lysate.
- Immunogen
- AIM2 (NP_004824, 1 a.a. ~ 343 a.a) full-length human protein.
- Top Product
- Discover our top product AIM2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- In 1x PBS, pH 7.4
- Handhabung
- Aliquot to avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells." in: Journal of virology, Vol. 87, Issue 15, pp. 8606-23, (2013) (PubMed).
: "Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers." in: Oncogene, Vol. 31, Issue 10, pp. 1242-53, (2012) (PubMed).
: "Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 11, pp. 1230-44, (2012) (PubMed).
: "AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA." in: Nature, Vol. 458, Issue 7237, pp. 509-13, (2009) (PubMed).
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Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells." in: Journal of virology, Vol. 87, Issue 15, pp. 8606-23, (2013) (PubMed).
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- Target
- AIM2 (Absent in Melanoma 2 (AIM2))
- Andere Bezeichnung
- AIM2 (AIM2 Produkte)
- Synonyme
- AIM2 antikoerper, PYHIN4 antikoerper, Gm1313 antikoerper, Ifi210 antikoerper, absent in melanoma 2 antikoerper, AIM2 antikoerper, Aim2 antikoerper
- Hintergrund
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Full Gene Name: absent in melanoma 2
Synonyms: PYHIN4 - Gen-ID
- 9447
- NCBI Accession
- NM_004833
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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