TREX1 Antikörper (AA 1-369)

Produktnummer ABIN524703

Produktdetails anti-TREX1 Antikörper

Target: TREX1 (three Prime Repair Exonuclease 1 (TREX1))

Bindungsspezifität: AA 1-369

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TREX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit polyclonal antibody raised against a full-length human TREX1 protein.

Sequenz: MGPGARRQGR IVQGRPEMCF CPPPTPLPPL RILTLGTHTP TPCSSPGSAA GTYPTMGSQA LPPGPMQTLI FFDMEATGLP FSQPKVTELC LLAVHRCALE SPPTSQGPPP TVPPPPRVVD KLSLCVAPGK ACSPAASEIT GLSTAVLAAH GRQCFDDNLA NLLLAFLRRQ PQPWCLVAHN GDRYDFPLLQ AELAMLGLTS ALDGAFCVDS ITALKALERA SSPSEHGPRK SYSLGSIYTR LYGQSPPDSH TAEGDVLALL SICQWRPQAL LRWVDAHARP FGTIRPMYGV TASARTKPRP SAVTTTAHLA TTRNTSPSLG ESRGTKDLPP VKDPGALSRE GLLAPLGLLA ILTLAVATLY GLSLATPGE

Kreuzreaktivität: Human, Maus

Produktmerkmale: Antibody reactive against mammalian transfected lysate.

Immunogen: TREX1 (NP_057465.1, 1 a.a. ~ 369 a.a) full-length human protein.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-TREX1 Antikörper (ABIN524703)

Tomicic, Aasland, Nikolova, Kaina, Christmann: "Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs." in: Biochimica et biophysica acta, Vol. 1833, Issue 8, pp. 1832-43, (2013) (PubMed).

Christmann, Tomicic, Aasland, Berdelle, Kaina: "Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage." in: Nucleic acids research, Vol. 38, Issue 19, pp. 6418-32, (2010) (PubMed).

Details zu TREX1

Target: TREX1 (three Prime Repair Exonuclease 1 (TREX1))

Andere Bezeichnung: TREX1 (TREX1 Produkte)

Synonyme: AGS1 antikoerper, CRV antikoerper, DRN3 antikoerper, HERNS antikoerper, 1661 antikoerper, AU041952 antikoerper, RGD1309596 antikoerper, three prime repair exonuclease 1 antikoerper, CpipJ_CPIJ012074 antikoerper, Tsp_03749 antikoerper, TREX1 antikoerper, Trex1 antikoerper

Hintergrund: Full Gene Name: three prime repair exonuclease 1
Synonyms: AGS1,AGS5,CRV,DKFZp434J0310,DRN3,HERNS

Gen-ID: 11277

NCBI Accession: NM_016381

Pathways: Apoptose