SMG1 Antikörper (AA 2922-3031)

Produktnummer ABIN524936

Produktdetails anti-SMG1 Antikörper

Target: SMG1 (pi-3-Kinase-Related Kinase SMG-1 (SMG1))

Bindungsspezifität: AA 2922-3031

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SMG1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant SMG1.

Sequenz: PDVMSQNARK LIQKNLATSA DTPPSTVPGT GKSVACSPKK AVRDPKTGKA VQERNSYAVS VWKRVKAKLE GRDVDPNRRM SVAEQVDYVI KEATNLDNLA QLYEGWTAWV

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: SMG1 (NP_055535, 2922 a.a. ~ 3031 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 1A8

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-SMG1 Antikörper (ABIN524936)

Arias-Palomo, Yamashita, Fernández, Núñez-Ramírez, Bamba, Izumi, Ohno, Llorca: "The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8." in: Genes & development, Vol. 25, Issue 2, pp. 153-64, (2011) (PubMed).

Stalder, Mühlemann: "Processing bodies are not required for mammalian nonsense-mediated mRNA decay." in: RNA (New York, N.Y.), Vol. 15, Issue 7, pp. 1265-73, (2009) (PubMed).

Details zu SMG1

Target: SMG1 (pi-3-Kinase-Related Kinase SMG-1 (SMG1))

Andere Bezeichnung: SMG1 (SMG1 Produkte)

Hintergrund: Full Gene Name: SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
Synonyms: 61E3.4,ATX,KIAA0421,LIP

Gen-ID: 23049

NCBI Accession: NM_014006

Pathways: Inositol Metabolic Process