LARP6 Antikörper (AA 1-491)

Produktnummer ABIN527496

Produktdetails anti-LARP6 Antikörper

Target: LARP6 (La Ribonucleoprotein Domain Family, Member 6 (LARP6))

Bindungsspezifität: AA 1-491

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser LARP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: Mouse polyclonal antibody raised against a full-length human LARP6 protein.

Sequenz: MAQSGGEARP GPKTAVQIRV AIQEAEDVDE LEDEEEGAET RGAGDPARYL SPGWGSASEE EPSRGHSGTT ASGGENERED LEQEWKPPDE ELIKKLVDQI EFYFSDENLE KDAFLLKHVR RNKLGYVSVK LLTSFKKVKH LTRDWRTTAH ALKYSVVLEL NEDHRKVRRT TPVPLFPNEN LPSKMLLVYD LYLSPKLWAL ATPQKNGRVQ EKVMEHLLKL FGTFGVISSV RILKPGRELP PDIRRISSRY SQVGTQECAI VEFEEVEAAI KAHEFMITES QGKENMKAVL IGMKPPKKKP AKDKNHDEEP TASIHLNKSL NKRVEELQYM GDESSANSSS DPESNPTSPM AGRRHAATNK LSPSGHQNLF LSPNASPCTS PWSSPLAQRK GVSRKSPLAE EGRLNCSTSP EIFRKCMDYS SDSSVTPSGS PWVRRRRQAE MGTQEKSPGT SPLLSRKMQT ADGLPVGVLR LPRGPDNTRG FHGHERSRAC V

Kreuzreaktivität: Human

Produktmerkmale: Antibody reactive against mammalian transfected lysate.

Immunogen: LARP6 (NP_060827, 1 a.a. ~ 491 a.a) full-length human protein.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-LARP6 Antikörper (ABIN527496)

Blackstock, Higashi, Sukhanov, Shai, Stefanovic, Tabony, Yoshida, Delafontaine: "Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA." in: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7264-74, (2014) (PubMed).

Wang, Stefanovic: "Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane." in: PLoS ONE, Vol. 9, Issue 10, pp. e108870, (2014) (PubMed).

Manojlovic, Blackmon, Stefanovic: "Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis." in: PLoS ONE, Vol. 8, Issue 6, pp. e65897, (2013) (PubMed).

Vukmirovic, Manojlovic, Stefanovic: "Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3893-906, (2013) (PubMed).

Manojlovic, Stefanovic: "A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs." in: RNA (New York, N.Y.), Vol. 18, Issue 2, pp. 321-34, (2012) (PubMed).

Challa, Stefanovic: "A novel role of vimentin filaments: binding and stabilization of collagen mRNAs." in: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3773-89, (2011) (PubMed).

Cai, Fritz, Stefanovic, Stefanovic: "Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen." in: Journal of molecular biology, Vol. 395, Issue 2, pp. 309-26, (2010) (PubMed).

Cai, Fritz, Stefanovic, Stefanovic: "Nonmuscle myosin-dependent synthesis of type I collagen." in: Journal of molecular biology, Vol. 401, Issue 4, pp. 564-78, (2010) (PubMed).

Details zu LARP6

Target: LARP6 (La Ribonucleoprotein Domain Family, Member 6 (LARP6))

Andere Bezeichnung: LARP6 (LARP6 Produkte)

Synonyme: im:7142825 antikoerper, wu:fa55b04 antikoerper, ACHN antikoerper, 5430431G03Rik antikoerper, AI552438 antikoerper, Achn antikoerper, RGD1308414 antikoerper, La ribonucleoprotein domain family, member 6b antikoerper, La ribonucleoprotein domain family member 6 antikoerper, La ribonucleoprotein domain family, member 6 antikoerper, larp6b antikoerper, LARP6 antikoerper, Larp6 antikoerper

Hintergrund: Full Gene Name: La ribonucleoprotein domain family, member 6
Synonyms: ACHN,FLJ11196

Gen-ID: 55323

NCBI Accession: NM_018357