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Glucosylceramidase Antikörper (N-Term)
GLCM
Reaktivität: Maus, Schwein, Kaninchen, Rind (Kuh), Ratte, Hund, Meerschweinchen, Pferd, Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5514399
Produktdetails anti-Glucosylceramidase Antikörper
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Target
Alle Glucosylceramidase (GLCM) Produkte
Glucosylceramidase (GLCM)
Bindungsspezifität
N-Term
Reaktivität
Maus, Schwein, Kaninchen, Rind (Kuh), Ratte, Hund, Meerschweinchen, Pferd, Human
Wirt
Kaninchen
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
Sequenz
FSSPSREECP KPLSRVSIMA GSLTGLLLLQ AVSWASGARP CIPKSFGYSS
Homologie
Cow: 75%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 75%, Pig: 79%, Rabbit: 75%, Rat: 75%
Produktmerkmale
This is a rabbit polyclonal antibody against GLCM. It was validated on Western Blot.
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLCM
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu Glucosylceramidase
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Target
Glucosylceramidase (GLCM)
Andere Bezeichnung
GLCM (GLCM Produkte )
Hintergrund
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. Alias Symbols: GBA, GC, GLUC, Protein Interaction Partner: NUDCD1, UBC, ITCH, ATP6V1B1, SNCA, FBXO6, TCP1, CBL, NEDD4, PARK2, HSP90AA1, HSPA4, PSAP, Protein Size: 536
Gen-ID
2629
NCBI Accession
XP_006711333
UniProt
P04062
Zuletzt angesehen
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