RNASEH2B Antikörper (C-Term)

Produktnummer ABIN5514417

Produktdetails anti-RNASEH2B Antikörper

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNASEH2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SKYLKLPEPS ASLPNPPSKK IKLSDEPVEA KEDYTKFNTK DLKTEKKNSK

Produktmerkmale: This is a rabbit polyclonal antibody against RNH2B. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RNH2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RNASEH2B

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Andere Bezeichnung: RNH2B (RNASEH2B Produkte)

Synonyme: AGS2 antikoerper, DLEU8 antikoerper, 1110019N06Rik antikoerper, 2610207P08Rik antikoerper, Dleu8 antikoerper, ribonuclease H2 subunit B antikoerper, ribonuclease H2, subunit B antikoerper, ribonuclease H2 subunit B L homeolog antikoerper, RNASEH2B antikoerper, Rnaseh2b antikoerper, rnaseh2b.L antikoerper

Hintergrund: RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

Alias Symbols: RNASEH2B, DLEU8,

Protein Interaction Partner: UBC, ANP32E, UBQLN2, RDX, DNAJB1, RNASEH2C, RNASEH2A, NRAS,

Protein Size: 312

Gen-ID: 79621

NCBI Accession: NP_078846

UniProt: Q5TBB1