PDE10A Antikörper (N-Term)

Produktnummer ABIN5514456

Produktdetails anti-PDE10A Antikörper

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE10A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SLHPQVLDEF VSESVSAETV EKWLKRKNNK SEDESAPKEV SRYQDTNMQG

Homologie: Dog: 93%, Horse: 93%, Human: 100%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PDE10A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDE10A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDE10A

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Andere Bezeichnung: PDE10A (PDE10A Produkte)

Hintergrund: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.

Alias Symbols: PDE10A,

Protein Interaction Partner: TOP1, UBC, WDR3, CASP3,

Protein Size: 779

Gen-ID: 10846

UniProt: Q9Y233

Pathways: cAMP Metabolic Process