RITA1 Antikörper (C-Term)
RITA1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
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- Target Alle RITA1 Produkte
- RITA1 (Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))
- Bindungsspezifität
- C-Term
- Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser RITA1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- TNGPQDLRPS TSGVTFRSPL VTSRARSVSI SVPSTPRRGG ATQKPKPPWK
- Produktmerkmale
- This is a rabbit polyclonal antibody against RITA1. It was validated on Western Blot.
- Aufreinigung
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human RITA1
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anti-Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1) antibody
RITA1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RITA1 (Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))
- Andere Bezeichnung
- RITA1 (RITA1 Produkte)
- Synonyme
- AI853657 antikoerper, C86297 antikoerper, Rita antikoerper, RBPJ interacting and tubulin associated 1 antikoerper, Rita1 antikoerper
- Hintergrund
-
RITA1 is a tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. It shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. And it may play a role in neurogenesis.
Alias Symbols: C12orf52, RITA, PSEC0043
Protein Size: 269 - Gen-ID
- 84934
- NCBI Accession
- XP_005254029
- UniProt
- Q96K30
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