CRYBB1 Antikörper (Middle Region)

Produktnummer ABIN5515282

Produktdetails anti-CRYBB1 Antikörper

Target: CRYBB1 (Crystallin, beta B1 (CRYBB1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYBB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SIIVSAGPWV AFEQSNFRGE MFILEKGEYP RWNTWSSSYR SDRLMSFRPI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CRYBB1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CRYBB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CRYBB1

Target: CRYBB1 (Crystallin, beta B1 (CRYBB1))

Andere Bezeichnung: CRYBB1 (CRYBB1 Produkte)

Synonyme: zgc:92706 antikoerper, CRYBB1 antikoerper, catcn3 antikoerper, Crybb1 antikoerper, CATCN3 antikoerper, CTRCT17 antikoerper, 3110006K12Rik antikoerper, BB1CRY antikoerper, CRYB1 antikoerper, CRYB11 antikoerper, crystallin, beta B1 antikoerper, crystallin beta B1 S homeolog antikoerper, crystallin beta B1 antikoerper, crybb1 antikoerper, crybb1.S antikoerper, CRYBB1 antikoerper, Crybb1 antikoerper

Hintergrund: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, undergoes extensive cleavage at its N-terminal extension during lens maturation. It is also a member of a gene cluster with beta-A4, beta-B2, and beta-B3.

Alias Symbols: CATCN3

Protein Interaction Partner: CRYBA1, TERF2IP, TERF1, CRYBB1, ABCC8,

Protein Size: 252

Gen-ID: 1414

NCBI Accession: NM_001887, NP_001878

UniProt: P53674