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DERL1 Antikörper (C-Term)
DERL1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5515996
Produktdetails anti-DERL1 Antikörper
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Target
Alle DERL1 Antikörper anzeigen
DERL1
(Der1-Like Domain Family, Member 1 (DERL1))
Bindungsspezifität
Alle Epitope für DERL1 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für DERL1 Antikörper
Human
Wirt
Alle Wirte für DERL1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für DERL1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für DERL1 Antikörper
Dieser DERL1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für DERL1 Antikörper
Western Blotting (WB)
Sequenz
STPQFLYRWL PSRRGGVSGF GVPPASMRRA ADQNGGGGRH NWGQGFRLGD
Produktmerkmale
This is a rabbit polyclonal antibody against DERL1. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human DERL1
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Discover our top product DERL1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu DERL1
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Target
DERL1
(Der1-Like Domain Family, Member 1 (DERL1))
Andere Bezeichnung
DERL1 (DERL1 Produkte )
Synonyme
CG10908 antikoerper, Dmel\\CG10908 antikoerper, DDBDRAFT_0188135 antikoerper, DDBDRAFT_0266772 antikoerper, DDB_0188135 antikoerper, DDB_0266772 antikoerper, MGC84200 antikoerper, wu:fb09d07 antikoerper, wu:fb94d05 antikoerper, wu:fj92g12 antikoerper, zgc:55637 antikoerper, 1110021N07Rik antikoerper, AI195141 antikoerper, AW551338 antikoerper, Derlin-1 antikoerper, derlin-1 antikoerper, DER-1 antikoerper, DER1 antikoerper, RGD1311835 antikoerper, DERLIN-1 antikoerper, F17A13.150 antikoerper, F17A13_150 antikoerper, Derlin-1 antikoerper, derlin-1 antikoerper, derlin-1.1 antikoerper, hypothetical protein antikoerper, Der1-like domain family, member 1 antikoerper, derlin 1 antikoerper, derlin 1 L homeolog antikoerper, DERLIN-1 antikoerper, Der-1 antikoerper, EDI_023440 antikoerper, PTRG_01331 antikoerper, derl1 antikoerper, DERL1 antikoerper, derl1.L antikoerper, Derl1 antikoerper, DER1 antikoerper
Hintergrund
The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. Alias Symbols: DERL1, DER1, UNQ243/PRO276, Protein Interaction Partner: HM13, TCF25, XBP1, EGFR, USP19, ZFAND2B, Vcp, PTGS2, CAV1, SYVN1, DERL2, SHH, SEL1L, SERPINA1, FAF2, ALB, APP, DERL1, EDEM1, RNF5, RHO, NGLY1, BCAP31, CFTR, UBXN6, TRAM1, APOB, CLN6, UBXN4, ERN1, ASGR2, UBE2J1, ERLIN2, UBC, HLA-A, CACNA1C, YOD1, VIMP, KPN Protein Size: 251
Gen-ID
79139
NCBI Accession
NP_077271
UniProt
Q9BUN8
Pathways
ER-Nucleus Signaling
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