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MAPK8IP1 Antikörper (Middle Region)
MAPK8IP1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5516520
Produktdetails anti-MAPK8IP1 Antikörper
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Target
Alle MAPK8IP1 Antikörper anzeigen
MAPK8IP1
(Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
Bindungsspezifität
Alle Epitope für MAPK8IP1 Antikörper
Middle Region
Reaktivität
Alle Reaktivitäten für MAPK8IP1 Antikörper
Human
Wirt
Alle Wirte für MAPK8IP1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für MAPK8IP1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für MAPK8IP1 Antikörper
Dieser MAPK8IP1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für MAPK8IP1 Antikörper
Western Blotting (WB)
Sequenz
VPRSQDTLNN NSLGKKHSWQ DRVSRSSSPL KTGEQTPPHE HICLSDELPP
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human MAPK8IP1
Top Product
Discover our top product MAPK8IP1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu MAPK8IP1
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Target
MAPK8IP1
(Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
Andere Bezeichnung
MAPK8IP1 (MAPK8IP1 Produkte )
Synonyme
IB1 antikoerper, JIP-1 antikoerper, Jip1 antikoerper, Prkm8ip antikoerper, Skip antikoerper, mjip-2a antikoerper, JIP1 antikoerper, Jip-1 antikoerper, Mapk8ip antikoerper, PRKM8IP antikoerper, mitogen-activated protein kinase 8 interacting protein 1 antikoerper, MAPK8IP1 antikoerper, Mapk8ip1 antikoerper
Hintergrund
This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. Alias Symbols: IB1, JIP1, JIP-1, PRKM8IP Protein Size: 711
Gen-ID
9479
NCBI Accession
NM_005456 , NP_005447
UniProt
Q9UQF2
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