FBXL15 Antikörper (N-Term)
FBXL15
Reaktivität: Human, Maus, Kaninchen, Ratte, Rind (Kuh), Hund, Ziege, Pferd
WB
Wirt: Kaninchen
Polyclonal
unconjugated
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- Target Alle FBXL15 Antikörper anzeigen
- FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Kaninchen, Ratte, Rind (Kuh), Hund, Ziege, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FBXL15 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PPMEPSGGEQ EPGAVRFLDL PWEDVLLPHV LNRVPLRQLL RLQRVSRAFR
- Homologie
- Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FBXL15. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15
- Top Product
- Discover our top product FBXL15 Primärantikörper
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anti-F-Box and Leucine-Rich Repeat Protein 15 (FBXL15) (AA 252-280), (C-Term) antibody
FBXL15 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB26324 unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
- Andere Bezeichnung
- FBXL15 (FBXL15 Produkte)
- Hintergrund
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FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.
Alias Symbols: FBXO37, Fbl15, JET, PSD
Protein Interaction Partner: HNRNPD, SKP1, ITCH, SMURF2, HECW2, SMURF1, NEDD4L, HECW1, WWP2, WWP1, RBX1, CUL1, NEDD4, HSP90AA1, COPS6, UBC,
Protein Size: 300 - Gen-ID
- 79176
- NCBI Accession
- NM_024326, NP_077302
- UniProt
- Q9H469
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