Tescalcin Antikörper (N-Term)
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- Target Alle Tescalcin (TESC) Antikörper anzeigen
- Tescalcin (TESC)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Tescalcin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LELNPIRSKI VRAFFDNRNL RKGPSGLADE INFEDFLTIM SYFRPIDTTM
- Produktmerkmale
- This is a rabbit polyclonal antibody against TESC. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human TESC
- Top Product
- Discover our top product TESC Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Tescalcin (TESC)
- Andere Bezeichnung
- TESC (TESC Produkte)
- Synonyme
- TSC antikoerper, chp3 antikoerper, CHP3 antikoerper, 1010001A17Rik antikoerper, 2410011K10Rik antikoerper, TE-1 antikoerper, RGD1566317 antikoerper, tescalcin antikoerper, tescalcin L homeolog antikoerper, tesc antikoerper, TESC antikoerper, Tesc antikoerper, tesc.L antikoerper
- Hintergrund
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TESC functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. It promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. It promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. It is essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. It is also involved in granulocytic differentiation in a ERK-dependent manner. It inhibits the phosphatase activity of calcineurin.
Alias Symbols: TESC, CHP3,
Protein Interaction Partner: WBP11, UBC, CCDC91, HMG20A, TESC, RAI1, DYNLT3, SLC9A1,
Protein Size: 214 - Gen-ID
- 54997
- NCBI Accession
- NP_060369
- UniProt
- Q96BS2
- Pathways
- Proton Transport
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