GSAP Antikörper (N-Term)
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- Target Alle GSAP (PION) Antikörper anzeigen
- GSAP (PION) (Pigeon Homolog (PION))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GSAP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- QTRQNELLYT FEKDLQVFSC SVNSERTLLA ASLVQSTKEG KRNELQPGSK
- Homologie
- Cow: 85%, Dog: 85%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GSAP. It was validated on Western Blot.
- Aufreinigung
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human GSAP
- Top Product
- Discover our top product PION Primärantikörper
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anti-Pigeon Homolog (PION) (AA 616-854) antibody
PION Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pigeon Homolog (PION) (AA 536-565), (C-Term) antibodyPION Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Pigeon Homolog (PION) (C-Term) antibodyPION Reaktivität: Human, Ratte, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GSAP (PION) (Pigeon Homolog (PION))
- Andere Bezeichnung
- GSAP (PION Produkte)
- Synonyme
- PION antikoerper, A530088I07Rik antikoerper, Pion antikoerper, gamma-secretase activating protein antikoerper, GSAP antikoerper, Gsap antikoerper
- Hintergrund
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Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease. Formation of amyloid-beta is catalyzed by gamma-secretase, a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein C-terminal fragment (APP-CTF).
Alias Symbols: GSAP, PION,
Protein Size: 854 - Gen-ID
- 54103
- NCBI Accession
- NP_059135
- UniProt
- A4D1B5
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